Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2015 Sep 12.

Published in final edited form as: Pediatr Res. 2014 Dec 17;77(3):447–454. doi: 10.1038/pr.2014.202

(A) Frozen sections of adipose from visceral and subcutaneous (SQ) depots were stained for CD40 (M1), CD206 (M2), and CD163 (M2), in 7 obese and 5 lean individuals. Representative samples are shown at 20× magnification.

(B) Obese visceral adipose shows a higher number of CD40⁺ macrophages than lean visceral adipose. In addition, obese subcutaneous adipose has a higher number of CD163⁺ macrophages than lean subcutaneous adipose. No significant differences were found for CD206⁺ macrophages. *P-values <0.05 determined by a two-sided Student’s t-test; error bars represent ±SEM; key: ■Lean SQ, □Lean Visceral, Obese SQ, Obese Visceral.

(C) The obese visceral adipose depot showed the highest M1:M2 ratio compared to every other condition.

Inline graphic — (A) Frozen sections of adipose from visceral and subcutaneous (SQ) depots were stained for CD40 (M1), CD206 (M2), and CD163 (M2), in 7 obese and 5 lean individuals. Representative samples are shown at 20× magnification.

(B) Obese visceral adipose shows a higher number of CD40⁺ macrophages than lean visceral adipose. In addition, obese subcutaneous adipose has a higher number of CD163⁺ macrophages than lean subcutaneous adipose. No significant differences were found for CD206⁺ macrophages. *P-values <0.05 determined by a two-sided Student’s t-test; error bars represent ±SEM; key: ■Lean SQ, □Lean Visceral, Obese SQ, Obese Visceral.

(C) The obese visceral adipose depot showed the highest M1:M2 ratio compared to every other condition.