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. Author manuscript; available in PMC: 2015 Sep 12.
Published in final edited form as: Pediatr Res. 2014 Dec 18;77(3):455–462. doi: 10.1038/pr.2014.209

Figure 4.

Figure 4

A: Representative photomicrograph of indomethacin (IND) and PGI2 effects on in vitro tube formation by PAEC from control and PPHN lambs. Tube length (B) and branch point number (C) were decreased in PPHN cells compared to control PAEC. Indomethacin decreases tube length (A and B) and branchpoint number in control PAEC (A and C). Decreased tube length (A&B) and branch point number (A&C) in PPHN was improved by adding PGI2 (100 pg/ml) to the medium.* p< 0.05 from untreated control PAEC and † from untreated PPHN cells. Open bar, untreated cells; filled bar, indomethacin treated and crosshatch, PGI2 treated cells. Scale bar=200 μ.