Table 1.
Epitope | Host | Cat# | Supplier | Dilution | Reference |
---|---|---|---|---|---|
anti-GFAP | Rabbit | Ab4674 | AbCam, Cambridge, MA | 1:2,000 | |
Anti-IP3R1 | Goat | sc-6093 | Santa Cruz Biotechnology, Santa Cruz, CA | 1:50 | (Payne et al., 2013a) |
Anti-IP3R2 | Goat | sc-7278 | Santa Cruz Biotechnology, Santa Cruz, CA | 1:50 | (Payne et al., 2013a) |
Anti-IP3R3 | Goat | sc-7277 | Santa Cruz Biotechnology, Santa Cruz, CA | 1:50 | (Payne et al., 2013a) |
anti-RyR1 | Rabbit | AB9078 | Chemicon; EMD Millipore, Bellerica, MA | 1:15,000 | (Medina-Ortiz et al., 2007; Payne et al., 2013a) |
anti-RyR2 | Rabbit | AB9080 | Chemicon; EMD Millipore, Bellerica, MA | 1:15,000 | (Medina-Ortiz et al., 2007; Payne et al., 2013a) |
anti-RyR3 | Rabbit | AB9082 | Chemicon; EMD Millipore, Bellerica, MA | 1:15,000 | (Medina-Ortiz et al., 2007; Payne et al., 2013a) |
We used the above subtype-specific antibodies to determine the localization and distribution of IP3Rs and RyRs in primary cultured rat ONHAs. All antibodies are well-characterized and their specificity for their respective epitopes has been shown previously.