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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Neurobiol Aging. 2014 Dec 12;36(3):1569–1576. doi: 10.1016/j.neurobiolaging.2014.11.017

Figure 5.

Figure 5

Striatal Protein levels of TH, GLT-1 and GFAP were altered in Gdnf+/− mice. (A) TH protein levels decreased in 12 mon Gdnf+/− mice from both 8 mon Gdnf+/− mice (*p<0.05) and 12 mon WT mice (**p<0.01). (B) GLT-1 protein levels were lower in 12 mon Gdnf+/− mice than either 8 mon Gdnf+/− mice (**p<0.01) or 12 mon WT mice (*p<0.05). (C) GFAP was increased predictably with age in both genotypes (WT: *p<0.05, Gdnf+/−: **p<0.01). GFAP levels were higher in Gdnf+/− mice at both ages compared to WT littermates (8 mon: *p<0.05, 12 mon: *p<0.05).