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. 2015 Feb 27;4(2):e33. doi: 10.1038/cti.2015.1

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Copyright © 2015 Australasian Society for Immunology Inc.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Line immunoblots demonstrating IgG antibody responses to six EBV proteins at five timepoints from the day before onset of illness (day −1) to 172 days postonset. Band intensities equal to or greater than the cutoff control are considered to indicate a specific antibody response. The first antibodies to appear are directed against BZLF1 (immediate early), and p23 (VCA). Antibodies to p138 and p54 (EA) developed next, followed by p18 (VCA) antibodies. Antibodies against EBNA-1 were seen only on the serum sample collected 172 days after onset of illness.