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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Neuropharmacology. 2015 Jan 14;92:80–89. doi: 10.1016/j.neuropharm.2015.01.002

Figure 7. PKC inhibition does not affect the paired-pulse ratio of excitatory and inhibitory PSCs in MSNs of the NAc shell.

Figure 7

(A) eEPSCs (top traces) or eIPSCs (bottom traces) evoked by a 10 Hz paired-pulse stimulus. Overlays of traces in the absence (thick black traces) and in the presence (thin gray traces) of PKC inhibition are pictured. Responses in each overlaid set of traces are normalized to the peak amplitude of the first pulse in the absence of PKC inhibition for ease of comparison. Stimulus artifacts were removed for illustration. (B) Paired-pulse ratios of eEPSCs (left) and eIPSCs (right) after PKC inhibition are plotted for D1DR- and D2DR-positive MSNs at indicated paired-pulse frequencies. No differences were found between any of the groups (n=8–9 cells from 3 animals).