. 2015 Jan 15;7(1):28–38.

Table 1.

Effect of treatment with adenine with or without addition of gum acacia (GA) on weight, total relative kidney weight (wt), water intake, urine and fecal output and food intake

PARAMETERS	CONTROL	ADENINE 50 (mg kg^-1)	ADENINE 50 (mg kg^-1) + GA	ADENINE 100 (mg kg^-1)	ADENINE 100 (mg kg^-1) + GA
Initial weight (gm)	216 ± 1.67^a	216 ± 7.51^a	217 ± 8.51^a	220 ± 1.63^a	215 ± 4.32^a
Final weight (gm)	224 ± 5.14^a	198 ± 7.9^b	218 ± 5.14^a	207 ± 3.12^a	208 ± 4.47^a
Bwt change %	3.44 ± 1.89^a	-4.7 ± 1.02^b	0.10 ± 1.81^a	-5.9 ± 1.91^b	-3.4 ± 0.79^b
Total kidney wt (gm)	1.27 ± 0.04^a	1.69 ± 0.03^a	1.28 ± 0.03^a	2.5 ± 0.21^b,c,d	1.48 ± 0.09^a,c,e
Relative kidney wt%	0.57 ± 0.02^a	1.02 ± 0.06^b	0.59 ± 0.01^a,c	1.24 ± 0.16^b,d	0.71 ± 0.04^a,e
Water intake (ml)	25.0 ± 2.71^a	28.6 ± 6.32^a	22.5 ± 1.54^a	46.3 ± 1.35^b,c,d	24.8 ± 1.92^a,e
Urine output (ml)	9.50 ± 0.67^a	21.2 ± 4.51^b	14.0 ± 1.54^a	31.8 ± 1.27^b,c,d	18.0 ± 0.81^a,e
Food intake (gm)	11.9 ± 0.57^a	15.3 ± 3.28^a	12.2 ± 1.05^a	13.8 ± 0.78^a	11.9 ± 0.36^a
Feces production (gm)	2.25 ± 0.19^a	5.13 ± 1.19^a	4.70 ± 0.52^a	5.61 ± 0.61^b	5.51 ± 0.25^b

Values are expressed as means ± SEM (n=6). Values (for the same parameter) with different superscript are significantly different (P<0.05 or less). Adenine was injected intraperitoneally (50 or 100 mg Kg^-1 for four weeks). GA was given in the drinking water at a concentration of 15% w/v for four weeks.