Table 2.
Sample | Amaxa (%, mean ± SD) | Tmaxb (minutes) | Cmaxc (ng/mL, mean ± SD) | C6d (ng/mL, mean ± SD) |
---|---|---|---|---|
A1 | 33.5 ± 6.6 | 15 | 198.7 ± 29.1 | 68.1 ± 7.6 |
B1 | 42.4 ± 2.8 | 15 | 249.2 ± 35.5 | 65.6 ± 17.3 |
C1 | 9.2 ± 3.6 | 30 | 52.9 ± 19.7 | 2.4 ± 3.4 |
A2 | 41.3 ± 2.0 | 15 | 137.5 ± 2.0 | BDL |
B2 | 32.7 ± 11.8 | 15 | 112.4 ± 41.5 | 18.2 ± 25.8 |
C2 | 16.1 ± 1.7 | 30 | 67.2 ± 7.3 | 10.6 ± 14.9 |
maximum amount (μg) measured in solution as a percentage of the initial amount of drug (μg)
time period at which maximum amount measured
maximum concentration (ng/mL) measured in solution
concentration (ng/mL) measured at the 6 hour time period
BDL = below detectable limit