Table 1. Inflammatory genes expressed in podocytes exposed to rSAA.

Discovery data sets				Validation data sets
Gene symbol	Gene name and/or description	P-value	RT2 Profiler Array	RT2 Profiler Array experiments, independent primers	Subsequent experiments
C3	Complement component 3	<0.001	24.4	25.4
Ccl2	MCP-1, monocyte chemoattractant protein-1, chemokine CC motif 2	<0.001	18.2	17.9	6.4
Ccl5	RANTES, regulated on activation, normal T-cell expressed and secreted, chemokine CC motif 5	<0.001	36.6	25.21	101.0
Ccl7	MCP-3, monocyte chemotactic protein-3, chemokine CC motif 7	<0.001	16.8	17.6
Ccl8	MCP-2, monocyte chemotactic protein-2, chemokine CC motif 8	0.002	22.6	21.0
Ccl17	TARC, thymus and activation-regulated chemokine CC motif 17	<0.001	3.4
Ccl19	MIP-3, macrophage inflammatory protein-3-beta, chemokine CC motif 19	0.013	−5.6
Ccl20	MIP-3, macrophage inflammatory protein-3-alpha, chemokine CC motif 20	<0.001	37.6
Cxcl1	GRO1, growth-related oncogene alpha chemokine CXC motif 1	<0.001	30.0	25.7
Cxcl2	GRO2, growth-related oncogene beta chemokine CXC motif 2	<0.001	28.3	16.0
Cxcl3	GRO3, growth-related oncogene gamma chemokine CXC motif 3	<0.001	8.5
Cxcl5	ENA-78, epithelial-derived neutrophil-activating protein 78, chemokine CXC motif 5	<0.001	166.1	52.5	18.5
Cxcl11	I-TAC, interferon-inducible T-cell alpha chemoattractant, chemokine CXC motif 11	0.003	3.6
Csf2	G-CSF2, granulocyte colony stimulating factor 2	<0.001	72.2
Csf3	G-CSF3, granulocyte colony stimulating factor 3	<0.001	34.2
Il1a	Interleukin-1	0.018	3.0
Il1rn	IL-1ra, interleukin-1 receptor antagonist	<0.001	5.3
Il-6	Interleukin 6	0.007	27.2
Itgb2	Cd18, integrin beta 2	<0.001	3.6
Kng1	Kng, kininogen1	0.003	10.0
Nos2	iNOS, nitric oxide synthase 2	<0.001	19.9	56.8	18.9
Ptgs2	Cox-2, prostaglandin-endoperoxide synthase 2	<0.001	3.3
Tlr5	Toll-like receptor 5	0.006	−7.4

Data are represented as fold change vs control.