Table 3.
The characteristics of VDR genetic variants in the studied subjects.
| SNPs | p.Gly14Ala | p.His305Gln | ||||||
|---|---|---|---|---|---|---|---|---|
| Genotype | GG | GC | CC | P | CC | CG | GG | P |
| Number (%) | 440 (0.4536) | 418 (0.4309) | 112 (0.1155) | — | 487 (0.5021) | 383 (0.3948) | 100 (0.1031) | — |
| Age (years) | 62.2 ± 7.2 | 62.5 ± 7.3 | 62.9 ± 6.9 | 0.553 | 61.9 ± 7.8 | 62.8 ± 7.0 | 62.9 ± 7.5 | 0.462 |
| Height (cm) | 161 ± 7.8 | 163 ± 6.8 | 164 ± 6.9 | 0.438 | 158 ± 7.8 | 162 ± 6.2 | 164 ± 6.9 | 0.538 |
| Weight (kg) | 62.4 ± 6.3 | 62.6 ± 6.5 | 62.8 ± 6.1 | 0.329 | 61.9 ± 7.7 | 62.7 ± 6.5 | 62.9 ± 6.5 | 0.365 |
| BMI | 23.2 ± 3.28 | 23.4 ± 3.35 | 23.7 ± 3.42 | 0.452 | 23.3 ± 3.67 | 23.6 ± 3.41 | 23.7 ± 3.53 | 0.239 |
| Lumbar spine BMD (g/cm2) | 0.932 ± 0.117 | 0.827 ± 0.122 | 0.822 ± 0.119 | 0.018 | 0.925 ± 0.113 | 0.832 ± 0.120 | 0.828 ± 0.126 | 0.028 |
| Femoral neck hip BMD (g/cm2) | 0.751 ± 0.125 | 0.687 ± 0.119 | 0.679 ± 0.128 | 0.037 | 0.749 ± 0.202 | 0.681 ± 0.197 | 0.679 ± 0.211 | 0.027 |
| Total hip BMD (g/cm2) | 0.865 ± 0.134 | 0.817 ± 0.156 | 0.809 ± 0.129 | 0.028 | 0.861 ± 0.129 | 0.820 ± 0.219 | 0.813 ± 0.172 | 0.048 |
Note: VDR: vitamin D receptor; SNPs: single nucleotide polymorphisms; BMD: bone mineral density; BMI: body mass index; Data are shown as mean ± SD (BMD values adjusted by age, weight, and height).