Fig. 3.

Effects of training on absolute response magnitudes (ARMs) and multiunit adaptation rates. The mean ARMs and adaptation rates of multiunit recording sites in NCM and CMM for subjects (n = 11) in response to GO, NoGO and novel auditory stimuli are shown. A: there was a significant main effect of training on ARMs in NCM (P < 0.05, repeated-measures ANOVA): responses were stronger for GO stimuli than NoGO stimuli (P < 0.05, Bonferroni post hoc test). B: there was also a significant main effect of training on ARMs in CMM (P < 0.0001, repeated-measures ANOVA). Here, novel stimuli evoked lower ARMs than reinforcement-predictive (GO and NoGO) stimuli did (P < 0.001 in both cases, Bonferroni post hoc test). In addition, multiunit adaptation rates showed main effects of training in NCM (P < 0.001, repeated-measures ANOVA) and CMM (P < 0.05, repeated-measures ANOVA). C: in NCM, NoGO stimuli were adapted to more slowly than GO (P < 0.01, Bonferroni post hoc test) and novel stimuli (P < 0.01, Bonferroni post hoc test). D: in CMM, NoGO stimuli were adapted to more slowly than GO stimuli (P < 0.05, Bonferroni post hoc test). Error bars depict within-subjects standard error. ARMs for representative multiunit responses (on trials 6–25) are shown for a novel, GO and NoGO stimulus for NCM (E) and CMM (F). Regression lines depict the adaptation of neural activity at each recording site. Brackets indicate significantly different comparisons.