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. 2014 Dec 24;308(5):L464–L478. doi: 10.1152/ajplung.00278.2014

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Fig. 2. — Immunoblot analysis of extracellular matrix (ECM) proteins in lungs of Eln^+/+ and Eln^+/− neonatal mice, showing increased abundance of collagen-1 (A) and lysyl oxidase proteins in Eln^+/− (B) pups; similar amounts of fibrillin-1 protein in Eln^+/+ and Eln^+/− pups (C); and less fibrillin-2 protein in Eln^+/− pups (D), compared with Eln^+/+ pups. Summary data; means and SD; *significant difference, P < 0.05. E: immunohistochemical localization of collagen-1 (arrows, brown stain) in lung sections of Eln^+/+ and Eln^+/− pups, showing prominent collagen-1 around microvessels, especially notable in the Eln^+/− lung (panel on right and inset). Lungs: ×400 magnification; insets: ×680 magnification; scale bar = 50 μm.