Table 2.
Evaluation of BALF cell differentials
| BALF Differential Cell Counts (% of Total Cells in BALF) |
||
|---|---|---|
| Alveolar macrophages | Neutrophils | |
| Untreated | ||
| CTL | 81.2 ± 6.0 | 15.2 ± 5.4 |
| Gamma | ||
| 1 Gy | 98.0 ± 1.0* | 2.0 ± 1.0* |
| 2 Gy | 94.5 ± 1.8 | 5.5 ± 1.8 |
| 3 Gy | 96.0 ± 1.0 | 4.0 ± 1.0 |
| Proton | ||
| 1 Gy | 90.2 ± 4.6 | 9.8 ± 5.4 |
| 2 Gy | 96.5 ± 1.2* | 3.5 ± 5.4* |
| 3 Gy | 94.0 ± 1.8 | 6.0 ± 5.4 |
| 56Fe Ions | ||
| 0.1 Gy | 82.4 ± 3.6 | 17.6 ± 3.6 |
| 0.2 Gy | 85.3 ± 3.4 | 14.7 ± 3.4 |
| 0.4 Gy | 91.4 ± 3.5 | 8.6 ± 3.5 |
| 1.0 Gy | 87.9 ± 7.4 | 12.1 ± 7.4 |
| 28Si Ions | ||
| 0.1 Gy | 94.6 ± 0.9 | 5.4 ± 0.9 |
| 0.2 Gy | 73.1 ± 6.4† | 26.9 ± 6.4† |
| 0.4 Gy | 88.2 ± 5.3 | 11.8 ± 5.3 |
| 1.0 Gy | 76.0 ± 4.0† | 24.0 ± 4.0† |
Abundance (percent of total cells) of alveolar macrophages and neutrophils in BALF from mice following exposure to the indicated sources and doses of radiation compared with controls (CTL). Total cells ± SE; N = 10/group.
*
Significant difference from untreated CTL;
†
significant difference from respective 0.1 Gy dose.