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. 2014 Dec 24;308(5):L429–L442. doi: 10.1152/ajplung.00285.2014

Fig. 2.

Fig. 2.

Mice deficient in functional Trx show increased mortality in hyperoxia. A: mice were exposed to 90% oxygen for 4 days followed by 3 days of recovery in room air (RA); Kaplan and Meier survival curve, P = 0.0084. B: amount of bronchoalveolar lavage fluid (BALF) protein is increased in WT or dnTrx-Tg mice but not in Trx-Tg mice exposed to hyperoxia. BALF protein is determined by Bradford protein assay. *Significant at P < 0.05, ANOVA. C: increased lung injury in hyperoxia in WT or dnTrx-Tg mice but not in Trx-Tg mice: lung tissue was fixed and processed as mentioned in materials and methods. The sections were processed for hematoxylin and eosin stain for observation of lung histopathology. The slides were observed under Zeiss Axioimager Z2.