Figure 1. Expressions of MUC5B in normal lung tissues and lung cancers.

Scattered cells with moderate to strong expression of MUC5B in bronchial epithelial cells (A). Strong staining was also found in bronchial glands (B). No obvious staining was observed in alveolar epithelial cells (C). Various extents of MUC5B expression in the cytoplasm of lung adenocarcinomas (D = well differentiated; E = moderately differentiated; F = poorly differentiated). The staining was almost completely absent in squamous cell carcinomas (G = well differentiated; H = moderately differentiated; I = poorly differentiated).