Table 2. Relationship Between MUC5B Expression and Clinicopathological Parameters in Lung Adenocarcinoma.
| MUC5B Expression | ||||
|---|---|---|---|---|
| Clinicopathological Parameters | Total | Positive Rate (%) | Ave. Score | P Value |
| Age, y | ||||
| <65 y | 109 | 64.2 | 4.5 | 0.4723 |
| ≥65 y | 89 | 66.3 | 3.9 | |
| Gender | ||||
| Male | 108 | 66.7 | 4.2 | 0.7934 |
| Female | 90 | 63.3 | 4.2 | |
| Smoking habit | ||||
| No | 93 | 60.2 | 4.1 | 0.4074 |
| Yes | 105 | 69.5 | 4.4 | |
| Tumor size | ||||
| ≤5 cm | 181 | 63.5 | 4.1 | 0.0693 |
| >5 cm | 17 | 82.4 | 5.9 | |
| Tumor differentiation | ||||
| Well/moderately | 168 | 63.1 | 3.9 | 0.0303 |
| Poorly | 30 | 76.7 | 5.9 | |
| p-TNM stage* | ||||
| Stage I | 130 | 59.2 | 3.7 | 0.0153 |
| Stage II/III | 68 | 76.5 | 5.1 | |
| Nodal status | ||||
| N0 | 152 | 61.8 | 4.0 | 0.0733 |
| N1/N2/N3 | 46 | 76.1 | 5.1 | |
| Vascular invasion | ||||
| No | 106 | 61.3 | 3.8 | 0.1352 |
| Yes | 69 | 70.0 | 4.9 | |
| Lymphatic invasion | ||||
| No | 101 | 66.3 | 4.2 | 0.5224 |
| Yes | 55 | 67.3 | 4.7 | |
| Pleural invasion | ||||
| No | 136 | 60.3 | 3.9 | 0.0867 |
| Yes | 62 | 75.8 | 4.8 | |
| Adjuvant chemotherapy | ||||
| No | 168 | 66.7 | 4.4 | 0.1959 |
| Yes | 30 | 56.7 | 3.2 | |
Data are presented as positive rate and average score. See Table 1 legend for expansion of abbreviations.
*Each case was reassigned for pathological stage according to the 7th edition of TNM classification[30, 31].