Table 3. Univariable and Multivariable Analysis for the effect of MUC5B Expression on Survival.

	Univariable Analysis			Multivariable Analysis
Factors	HR	95% CI	P Value	HR	95% CI	P Value
MUC5B expression
High (≥9) vs low (<9)	2.794	1.434–5.444	0.0025	2.658	1.260–5.608	0.0102
Age
≥65 vs <65	1.046	0.555–1.969	0.8902	n/d	n/d	n/d
Gender
Male vs female	1.384	0.726–2.639	0.3232	n/d	n/d	n/d
Smoking habit
No vs Yes	1.525	0.800–2.907	0.1999	n/d	n/d	n/d
Tumor size
≤5 cm vs >5 cm	6.175	3.000–12.711	<0.0001	3.808	1.537–9.435	0.0039
p-TNM stage
Stage II/III vs stage I	9.526	4.373–20.749	<0.0001	2.650	1.107–6.344	0.0287
Adjuvant chemotherapy
No vs yes	6.751	3.585–12.711	<0.0001	4.043	2.213–9.872	0.0001
Tumor differentiation
Poorly vs well/moderately	3.363	1.701–6.648	0.0005	n/d	n/d	n/d
Vascular invasion
No vs Yes	10.004	4.146–24.141	<0.0001	3.889	1.465–10.323	0.0064
Lymphatic invasion
No vs Yes	5.046	2.387–10.668	<0.0001	n/d	n/d	n/d
Pleural invasion
No vs Yes	2.935	1.563–5.511	0.0008	n/d	n/d	n/d

n/d: not done.