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. 2015 Mar 3;5:8705. doi: 10.1038/srep08705

Figure 2. SMaRT-mediated repair of mutant p53 transcripts resulted in the induction of the apoptosis in PLC/PRF/5 cells.

Figure 2

(A). SMaRT induced the apoptosis of PLC/PRF/5 cells determined by TUNEL Staining. (B). Cell apoptosis was detected by Annexin-V/propidium iodide combined labeling flow cytometry in PLC/PRF/5 cells. * p < 0.05. (C). mRNA relative expression of p53-responsive apoptotic genes was measured by SYBR Green qRT-PCR. * p < 0.05. (D). Representative Western blot and densitometric quantification of the proteins involved in apoptosis were shown.