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. 2015 Mar 3;5:8718. doi: 10.1038/srep08718

Figure 6. MSC-CMIEC-6(IR) down-regulates radiation-induced inflammatory responses at systemic and musocal level.

Figure 6

(A) The levels of pro/anti-inflammatory cytokines in jejunal protein extracts 3 days after radiation were determined by enzyme-linked immunosorbent assay (ELISA). n = 4 rats/group. **, P < 0.05 versus IR + DMEM-F12, ##, P < 0.05 versus IR + MSC-CMIEC-6(NOR). (B) ELISA assays for serum pro/anti-inflammatory cytokines in rats of the 4 treatment groups are shown. Serum samples were collected 3 days after radiation. n = 4 rats/group, **, P < 0.05 versus IR + DMEM-F12, ##, P < 0.05 versus IR + MSC-CMIEC-6(NOR). (C) The percentages of CD4+Foxp3+ Treg cells in the CD4+ population of mesenteric lymph nodes (MLNs) were determined by flow cytometry (4–5 rats/group). Tissue samples were collected 3 days after radiation. **, P < 0.05 versus IR + DMEM-F12, ##, P < 0.05 versus IR + MSC-CMIEC-6(NOR).