Figure 4. NanoPET/CT study of subcutaneous BGC-823 tumor-bearing nude mice after intravenous (i.v.) injection of 7.4 MBq of ⁶⁸Ga-NOTA-MG7.

(a). Decay-corrected whole-body nanoPET/CT images of nude mice bearing BGC-823 tumor at 30, 60 and 90 min pi. (b). Blocking experiment with co-injection of 20 mg/kg of MG7 antibody at 30, 60 and 90 min pi. (c). Time–activity curves (TACs) of the tumor, kidney, liver and muscle after intravenous (i.v.) injection of ⁶⁸Ga-NOTA-MG7. (d). Time–activity curves (TAC) of the tumor, kidney, liver and muscle after co-injection with MG7 antibody (20 mg/kg of mouse body weight). ROIs are shown as the mean%ID/g ± SD (n = 3/group).