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. 2015 Mar 3;5:8693. doi: 10.1038/srep08693

Figure 2. Infection response genes in the Pacific oyster, Crassostrea gigas.

Figure 2

(a), Venn diagrams of differentially expressed genes under the challenge of LPS, Gram positive bacteria M. lut (Micrococcus luteus), Five types of Vibrio (V. anguillarum, V. tubiashii, V. aestuarianus, V. alginolyticus-1, V. alginolyticus-2), and OsHV-1 (ostreid herpesvirus). (b), Major pathways enriched for the up-regulated genes under seven types of pathogen and LPS challenges. I. Cell adhesion related; II. Cellular protein homeostasis; III. Amino acid metabolism; IV. Lipoic acid metabolism; V. Host immune defense. (c), (Left) Unique and differentially expressed genes infected with four types of Vibrio administered separately and simultaneously; (Right) Unique and differentially expressed genes infected with two strains of V. alginolyticus. (d), The three most enriched domain types of up-regulated transcripts generated by pairwise comparison of seven types of pathogens and LPS challenges vs PBS challenge. Three different colors represent three different enriched domains. The x axis is the – log 2 transformation of the p-value calculated in the enrichment test.