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. 2015 Jan 22;16(2):2294–2306. doi: 10.3390/ijms16022294

Table 1.

Correlation between F-box and WD repeat domain-containing 7 (FBXW7) expression and the clinicopathological characteristics of the osteosarcoma (OS) patients.

Clinicopathologic Features Total No. of Patients, n = 68 No. of Patients p
Low FBXW7 High FBXW7
Gender Male 40 19 21 0.622
Female 28 15 13
Age (years) <24 49 24 25 0.787
≥25 19 10 9
Clinical stage I 27 9 18 <0.001 *
II 34 18 16
III 7 7 0
T classification T1 26 9 17 0.046 *
T2 42 25 17
M classification M0 61 29 32 0.427
M1 7 5 2
Histology Conventional osteosarcoma 58 28 30 0.493
Others 10 6 4
Histological differentiation G1 27 8 19 0.006 *
G2 41 26 15

T, tumor; M, metastasis; * Statistically significant.