Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 26;16(2):2678–2692. doi: 10.3390/ijms16022678

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Peripherin 2 (red) and rhodopsin (green) expression in retinal pigment epithelium (RPE) of representative healthy (left) and ERU cases (right). Differential interference contrast image of healthy (A) and diseased (E) equine RPE. In healthy (B) RPE, peripherin 2 was expressed over the entire RPE cell layer, and the intensity was enhanced in some spots. In uveitic RPE cells (F), peripherin 2 was significantly reduced to few small spots; Rhodopsin was limited to few isolated spots, distributed throughout the whole RPE layer, in healthy (C), as well as in diseased (G) RPE. The overlap of peripherin 2 and rhodopsin in healthy (D) RPE indicates significant higher expression of peripherin 2 compared to rhodopsin (the yellow overlap is only displayed in a few spots). In uveitic RPE (H), peripherin 2 was only expressed at rhodopsin expression sites (yellow spots).