Table 2.
Genotype distribution of the SNPs and their associations with the risk of CHF under different contrast models.
| Genotype | Controls n (%) | CHF n (%) | HWE p a | Dominant Model p a | Recessive Model p a | Additive Model p a | Allele Contrast p a |
|---|---|---|---|---|---|---|---|
| rs2236624 | 0.752 | 0.842 | 0.223 | 0.390 | 0.381 | ||
| TT (W) | 33 (8.27) | 26 (8.70) | |||||
| CT | 159 (39.85) | 104 (34.78) | |||||
| CC | 207 (51.88) | 169 (56.52) | |||||
| rs2236625 | 0.319 | 0.699 | 0.443 | 0.433 | 0.932 | ||
| CC (W) | 312 (78.39) | 238 (79.60) | |||||
| CT | 83 (20.85) | 56 (18.73) | |||||
| TT | 3 (0.75) | 5 (1.67) | |||||
| rs4822489 | 0.219 | 0.450 | 0.729 | 0.609 | 0.814 | ||
| TT (W) | 98 (24.69) | 66 (22.22) | |||||
| GT | 186 (46.85) | 150 (50.51) | |||||
| GG | 113 (28.46) | 81 (27.27) | |||||
| rs5751876 | 0.996 | 0.818 | 0.445 | 0.650 | 0.725 | ||
| TT (W) | 90 (22.67) | 70 (23.41) | |||||
| CT | 198 (49.87) | 139 (46.49) | |||||
| CC | 109 (27.46) | 90 (30.10) | |||||
| rs7208480 | <0.001 | 0.283 | 0.555 | 0.760 | 0.322 | ||
| CC (W) | 197 (49.25) | 135 (45.15) | |||||
| CT | 195 (48.75) | 156 (52.17) | |||||
| TT | 8 (2.00) | 8 (2.68) |
Abbreviations: CHF, chronic heart failure; HWE, Hardy–Weinberg equilibrium. a p values were calculated from a two-sided χ2-test.