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. 2015 Jan 28;16(2):2879–2892. doi: 10.3390/ijms16022879

Figure 1.

Figure 1

Schematic illustration of tumor suppressor signaling including BRCA1, p53, Rb, p21WAF1/p27KIP1, and ATM in Alzheimer’s disease. Examples of molecules involved in Alzheimer’s disease known to act on cell growth arrest and DNA repair via the regulatory pathways are presented. Note that some critical pathways have been omitted for clarity.