Table 2.
Differentially expressed unigenes encoding enzymes in the ginsenoside biosynthesis pathway.
| Ginsenoside Biosynthesis Steps | Name of Enzymes | Number of Unigenes | Up-Regulated | Down-Regulated | Not DEGs |
|---|---|---|---|---|---|
| Step I | AACT | 3 | 1 | 2 | - |
| HMGS | 9 | 2 | 7 | - | |
| HMGR | 15 | 4 | 11 | - | |
| MVK | 20 | 14 | 6 | - | |
| PMK | 16 | 10 | 6 | - | |
| MDD | 2 | 1 | 1 | - | |
| IDI | 2 | 1 | 1 | - | |
| Step II | GPS | 24 | 8 | 16 | - |
| FPS | 1 | 1 | 0 | - | |
| GGPPS | 14 | 6 | 8 | - | |
| SS | 10 | 10 | 0 | - | |
| SE | 11 | 7 | 4 | - | |
| Step III | DDS | 1 | 1 | 0 | - |
| β-AS | 9 | 2 | 7 | - | |
| CAS | 17 | 1 | 16 | - | |
| LS | 2 | 0 | 2 | - | |
| P450 | 335 | 161 | 168 | 6 | |
| GT | 142 | 48 | 92 | 2 | |
| UGT | 116 | 71 | 45 | - |
AACT, acetyl-CoA acetyltransferase; HMGS, HMG-CoA synthase; HMGR, HMG-CoA reductase; MVK, mevalonate kinase; PMK, phosphomevalonate kinase; MDD, mevalonate-5-diphosphate decarboxylase; IDI, isopentenyl diphosphate isomerase; GPS, geranyl diphosphate synthase; FPS, farnesyl diphosphate synthase; GGPPS, geranylgeranyl diphosphate synthase; SS, squalene synthase; SE, squalene epoxidase; DDS, dammarenediol synthase; β-AS, beta-amyrin synthase; CAS, cycloartenol synthase; LS, lanosterol synthase; P450, cytochrome P450; GT, glycosyltransferase; UGT, UDP-glycosyltransferase; DEGs, differentially expressed genes.