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Schematic implication of protein kinases PKA and AKT modulation in the pathogenesis of autisms and ADHD. Alteration of the functions in neurobeachin, CADM1 and DAT with genetic deletion and/or single nucleotide polymorphisms (SNPs) may change the activity or selectivity of kinase to substrates, which in turn may cause the psychological disorders. Star faces represent an image of the individual kinase activities. Sad faces mean unbalance of kinase activity.
