Table 4.
Literature Review of Behavioral and Psychiatric Problems for Individuals with Chromosome 15q11.2 BP1–BP2 Microdeletion Syndrome.
| Feature | Murthy et al. [15] | Doornbos et al. [16] | Von der Lippe et al. [34] | Burnside et al. [13] | Abdelmoity et al. [17] | Madrigal et al. [33] | Cafferkey et al. [18] | Rudd et al. [37] | Jerkovich & Butler [14] | Total (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| General behavior problems, unspecified | 2/2 | N/A | N/A | 35/56 | N/A | 2/4 | 35/73 | N/A | 1/1 | 75/136 (55) |
| Autism Spectrum Disorder | 1/2 | 4/9 | 1/7 | 14/49 | 2/16 | 2/4 | 19/73 | N/A | 0/1 | 43/161 (27) |
| Schizophrenia/paranoid psychosis | N/A | 0/9 | 1/7 | N/A | N/A | N/A | N/A | 3/3 | 0/1 | 4/20 (20) |
| OCD 1 | 0/2 | 2/9 | 0/7 | 16/49 * | N/A | N/A | N/A | N/A | 0/1 | 18/68 (26) |
| ODD 2 | 0/2 | 0/9 | 0/7 | 16/49 * | N/A | N/A | N/A | N/A | 0/1 | 16/68 (24) |
| ADD 3/ADHD 4 | 2/2 | 2/9 | 0/7 | 16/49 | 7/12 | N/A | N/A | N/A | 1/1 | 28/80 (35) |
| Self-injurious behaviors | 0/2 | 2/9 | 0/7 | 16/49 * | N/A | N/A | N/A | N/A | 0/1 | 18/68 (26) |
| Anxiety | N/A | 0/9 | 1/7 | N/A | N/A | N/A | N/A | N/A | 0/1 | 1/17 (6) |
| Happy expression | N/A | 2/9 | 0/7 | N/A | N/A | N/A | N/A | N/A | 0/1 | 2/17 (12) |
1 Obsessive compulsive disorder; 2 Oppositional defiant disorder; 3 Attention deficit disorder; 4 Attention deficit hyperactivity disorder; * indicates obsessive compulsive disorder, oppositional defiant disorder, self-injury, tantrums, etc; Bold indicate categories that represent 50% or greater incidence within the literature.