Figure 1.

Immunoreactivity of ET-1, ET_A and ET_B in COH retina compared to the normal.

The immunoreactivity of ET-1 was increased at 1-month and 2-month in COH (B, C) when compared with the normal (A); the immunoreactivity of ET_A receptor was decreased at 1-month and 2-month in COH (E, F) when compared with the normal (D) and the immunoreactivity of ET_B receptor was increased at 1-month and 2-month in COH (H, I) when compared with the normal (G). Scale bar: 20 μm, n = 3.

ET-1: Endothelin-1; ET_A: endothelin A receptor; ET_B: endothelin B receptor; GCL: ganglion cell layer; IPL: inner plexiform layer; INL: inner nuclear layer; ONL: outer nuclear layer; COH: chronic ocular hypertension.