[Table/Fig-2]:
Baseline characteristics of study subjects
| S. No. | Baseline characteristics | Ranolazine 500 mg BD (N=23) | Trimetazidine 35 mg BD (N=24) |
|---|---|---|---|
| 1 | Age (yrs) | 58 ± 8.1 | 57.4 ± 9.1 |
| 2 | Male (%): Female (%) | 18 (78.3): 5 (21.7) | 21 (87.5): 3 (12.5) |
| 3 | BMI (Kg/m2) | 24.9 ± 3.1 | 26.2 ± 3.1 |
| 4 | †Duration of CAD (months) | 28.1 ± 29 | 42 ± 41.1 |
| 5 | †Duration of DM (months) | 91.2 ± 80.1 | 66.2 ± 56.9 |
| 6 | HbA1c (%) | 9.2 ± 1.7 | 8.5±1.4 |
| 7 | †Fasting blood glucose (mg/dl) | 168.5 ± 49.3 | 148.2 ± 59 |
| 8 | Post prandial blood glucose (mg/dl) | 284.5 ± 85.8 | 239.9 ± 77.1 |
| 9 | QT (ms) | 359.8 ± 28.8 | 356.3 ± 32.7 |
| 10 | QTc (ms) | 401.1 ± 42.2 | 396.3 ± 38.2 |
| 11 | HR (bpm) | 76.5 ± 15.8 | 74.8 ± 14.6 |
| 12 | †SBP (mmHg) | 128.6 ± 19.5 | 130.5 ± 21.9 |
| 13 | †DBP (mmHg) | 80.1 ± 14 | 82 ± 11.6 |
| 14 | Urea (mg/dl) | 25.2 ± 8.3 | 27.3 ± 9.6 |
| 15 | †Creatinine (mg/dl) | 0.9 ± 0.3 | 1.1 ± 0.4 |
| 16 | †Frequency of angina / wk | 1.6 ± 5.8 | 1.8 ± 4.5 |
| 17 | † Isosorbide dinitrate consumption / wk | 1.7 ± 3.1 | 2.5 ± 7.7 |
| 18 | Total cholesterol (mg/dl) | 158.9 ± 33.5 | 149.1 ± 37 |
| 19 | †Triglycerides (mg/dl) | 167.7 ± 128 | 142.5 ± 60.4 |
| 20 | †High density lipoprotein (mg/dl) | 37.4 ± 18.1 | 34 ± 9.4 |
| 21 | Low density lipoprotein (mg/dl) | 93.4 ± 20.3 | 92.6 ± 33.2 |
| 22 | †Very low density lipoprotein (mg/dl) | 31.1 ± 20.8 | 28.2 ± 12 |
Values are expressed as mean ± SD (Standard deviation)
†Mann Whitney U test (Non parametric test used as Kolmogorov and Smirnov normality was not passed)