[Table/Fig-1]:

Diagnostic criteria for Guillain-Barre syndrome after Asbury and Cornblath [5]

*CSF=cerebrospinal fluid

I. Features required for diagnosis

(A) Progressive motor weakness of more than one limb

(B) Loss of tendon jerks

II. Features strongly supportive of the diagnosis

(A) Clinical features

1. Progression over four weeks

2. Relative symmetry of weakness

3. Mild sensory symptoms or signs

4. Cranial nerve involvement

5. Recovery, usually beginning two to four weeks after progression stops

6. Autonomic dysfunction

7. Absence of fever at the onset of neuritic symptoms

(B) CSF* features

1. CSF protein raised after the first week of symptoms

2. Counts of 10 or fewer mononuclear leucocytes x 106/1

(C) Electrodiagnostic features

Reduction of conduction velocity, conduction block or abnormal temporal dispersion, increased distal latency or abnormal F wave in more than one nerve

III. Features casting doubt on the diagnosis

(A) Marked, persistent asymmetry of weakness

(B) Persistent bladder or bowel dysfunction

(C) Bladder or bowel dysfunction at onset

(D) More than 50 mononuclear leucocytes x 106/1 in CSF

(E) Presence of polymorphonuclear leucocytes in CSF

(F) Sharp sensory level

IV. Features that rule out the diagnosis

(A) Indication of any metabolic, infectious, or toxic disease associated with Polyneuropathy

(B) Occurrence of a purely sensory syndrome