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. 2014 Oct 8;124(11):4965–4975. doi: 10.1172/JCI75660

Figure 6. Contribution of IL-1, IL-6, and IL-33 to Th2 and Tfh induction by SEB.

Figure 6

4get mice were pretreated with either isotype control or (A and B) neutralizing IL-6 antibodies plus IL-1 receptor antagonist or (C and D) neutralizing anti-ST2 antibody before epicutaneous exposure to SEB. Draining lymph nodes and mesenteric lymph nodes were harvested 1 week later. Summary plots of (A and C) IL-4+ cells or (B and D) CXCR5+ICOS+ cells per million CD4+ T cells are shown. Data are mean ± SEM of 3 mice per condition. *P < 0.05, **P < 0.01.