Figure 6. Development of BO is dependent on ITK expression in donor mature T cells.

(A) Day 60 PFTs from mice transplanted with WT BM and low numbers of either WT T cells or ITK-deficient T cells. (B) Pathologic scores in lung and (C) liver of day 60 transplanted mice. n = 5 mice/group in 2 independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001.