Table 1. Performance of Three Readers for Characterization of Breast Lesions at DBT and US.

	Az Value				Sensitivity* (%)			Specificity* (%)
	DBT	US	95% CI†	P	DBT	US	P	DBT	US	P
Reader 1	0.896	0.935	-0.014, 0.094	0.150	98.7 (74/75)	100 (75/75)	1.000	36.4 (16/44)	43.2 (19/44)	0.581
Reader 2	0.917	0.905	-0.038, 0.062	0.648	100 (75/75)	98.7 (74/75)	1.000	25.0 (11/44)	31.8 (14/44)	0.549
Reader 3	0.932	0.911	-0.036, 0.077	0.480	93.3 (70/75)	97.3 (73/75)	0.453	72.7 (32/44)	43.2 (19/44)	0.004
Overall	0.899	0.914	-0.019, 0.049	0.394	97.3	98.7	0.508	44.7	39.4	0.360

Note.- ^*Data in parentheses were used to calculated percentages. Optimal cut-off, between Breast Imaging Reporting and Data System category 3 and 4A was used to yield maximal sum of sensitivity and specificity in both modality, ^†CI = confidence interval for difference between DBT and US. DBT = digital breast tomosynthesis, US = ultrasound