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Obesity down-regulates the expression of genes of BCAA metabolism. Schematic diagram of cellular BCAA metabolism (A) and expression of BCAA metabolism genes in epididymal (B) or inguinal white adipose tissue (C) in C57BL/6J mice maintained on a low-fat (filled bars) or high-fat (open bars) diet. D, Expression of BCAA metabolism genes in brown adipose tissue, liver, and gastrocnemius skeletal muscle tissue. Error bars represent SEM. *, P < .05 (n equals 6–12 per group).
