Figure 3.

MBL-associated serine protease (MASP)-2-deficiency does not increase susceptibility to T. cruzi infection. (A) Parasitemia curves of 15 wild-type (WT) and 6 MASP-2-def mice infected with T. cruzi trypomastigotes (Figure 2) were compared between mice groups by two-way analysis of variance followed by Sidak's analysis for multiple comparisons. The results represent the mean ± SE values. (B) Kaplan-Meier curves for survival rates of trypomastigote-infected WT and MASP-2-deficient mice. Log-rank test was used to compare survival curves. All data were analyzed with GraphPad Prism software.