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. 2015 Feb 4;92(2):370–376. doi: 10.4269/ajtmh.14-0455

Table 5.

Neutralizing Ab titers to inoculated DENV-2 (DHF0663 strain) in marmosets using BHK and FcγR-expressing BHK cells

Animal identification Days after inoculation (PRNT50 titers by BHK, FcγR-expressing BHK cells)
0* 2 4 7 11 15 21
Group A (mAb 4G2)
 A1 < 10, < 10 < 10, < 10 < 10, < 10 10, 10 10, 10 10, 10 20, 10
 A2 < 10, < 10 < 10, < 10 < 10, < 10 10, < 10 10, 20 10, 10 10, ND
 A3 < 10, < 10 < 10, < 10 < 10, < 10 10, < 10 20, 20 10, 10 10, 10
Group B (mAb 6B6C)
 B1 10, < 10 10, < 10 10, < 10 10, < 10 10, 10 ND, 10 40, 10
 B2 10, < 10 10, < 10 < 10, < 10 < 10, < 10 ND, ND 10, 10 40, 10
 B3 < 10, < 10 < 10, < 10 10, < 10 10, < 10 10, 20 20, 10 10, ND
Control (saline)
 C1 < 10, < 10 < 10, < 10 < 10, < 10 < 10, < 10 20, 20 10, 10 20, 10
 C2 < 10, < 10 < 10, < 10 < 10, < 10 10, 10 ND, ND 10, 10 160, 10
 C3 < 10, < 10 < 10, < 10 < 10, < 10 10, < 10 ND, ND 10, 10 40, 20
 C4 < 10, < 10 < 10, < 10 < 10, < 10 10, < 10 ND, ND 10, 10 80, 40

Results are shown as reciprocal of the highest plasma dilution (end-point titer) that results in < 50% input of plaque count and were expressed as PRNT50 values. ND = not determined because of low sample volumes.

*

Values after Ab or saline administration.