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. 2015 Jan 7;92(1):172–177. doi: 10.4269/ajtmh.14-0418

Table 3.

Factors associated with in-hospital mortality among all patients with documented or reported fever (N = 429)

n Unadjusted OR (95% CI) P value AOR* (95% CI) P value
Age (years) 412 1.00 (0.98–1.01) 0.61
Male 429 1.51 (0.89–2.54) 0.13
Dry season 429 1.23 (0.77–1.96) 0.39
Headache 426 0.81 (0.49–1.33) 0.41
Cough 425 1.11 (0.67–1.82) 0.69
Dyspnea 400 1.10 (0.62–1.95) 0.74
Abdominal pain 412 1.59 (0.97–2.61) 0.07 1.55 (0.83–2.88) 0.17
Vomiting 425 1.56 (0.95–2.57) 0.08 1.08 (0.57–2.05) 0.81
Dizziness 422 1.42 (0.87–2.34) 0.16
Anorexia 392 1.37 (0.80–2.35) 0.26
Weight loss 379 1.08 (0.53–2.20) 0.84
Temperature ≥ 38°C 394 2.67 (1.56–4.57) < 0.001 2.89 (1.58–5.26) 0.001
Pulse (beats/minute) 402 1.01 (0.99–1.02) 0.28
Systolic blood pressure < 90 mmHg 395 4.26 (2.01–9.07) < 0.001 2.35 (0.94–5.89) 0.07
Diastolic blood pressure < 60 mmHg 393 1.59 (0.65–3.92) 0.31
Respirations per minute 344 1.00 (0.99–1.02) 0.71
WBC count (× 103 cells/μL) 173 1.00 (1.00–1.00) 0.66
Hemoglobin (g/dL) 315 0.80 (0.71–0.90) < 0.001
Creatinine (μM/L) 163 1.00 (1.00–1.01) 0.10
Malaria parasite density (parasites/μL) 292 1.00 (1.00–1.00) 0.94
Unknown diagnosis 429 1.98 (1.19–3.28) 0.01 2.04 (1.09–3.80) 0.03
Malaria 429 0.66 (0.37–1.18) 0.16
Lassa fever 429 2.82 (1.13–7.06) 0.03 2.26 (0.47–10.81) 0.31
Pneumonia 429 0.42 (0.10–1.81) 0.24
Length of hospitalization (days) 422 0.85 (0.79–0.91) < 0.001 0.89 (0.82–0.96) 0.002
*

Adjusted model sample size equals 357 and includes the following covariates: abdominal pain, vomiting, febrile, systolic BP < 90 mmHg, unknown diagnosis, and length of hospitalization.