Table 1.
Baseline demographic, clinical, and laboratory characteristics of study participants
| Dengue NS1 test positive (N = 23) | Dengue NS1 test negative (N = 111) | P value | |
|---|---|---|---|
| Male sex | 15/23 (65.2) | 61/111 (55.0) | 0.49 |
| Children | 9/23 (39.1) | 43/111 (38.7) | > 0.99 |
| Chills and rigors | 18/23 (78.3) | 58/103 (56.3) | 0.06 |
| Vomiting | 11/ 23 (47.8) | 23/104 (22.1) | 0.02 |
| Headache | 20/23 (87.0) | 70/98 (71.4) | 0.18 |
| Flushing of the face | 16/23 (69.6) | 57/101 (56.4) | 0.35 |
| Eye redness | 11/23 (47.8) | 52/103 (50.5) | > 0.99 |
| Rash | 2/23 (8.7) | 16/100 (16.0) | 0.52 |
| Dark urine | 0/23 (0.0) | 1/103 (1.0) | > 0.99 |
| Diarrhea | 4/23 (17.4) | 15/100 (15.0) | 0.75 |
| Enlarged cervical glands | 1/23 (4.3) | 13/100 (13.0) | 0.47 |
| Myalgia | 18/23 (78.3) | 65/94 (69.1) | 0.45 |
| Arthralgia | 18/23 (78.3) | 71/94 (75.5) | > 0.99 |
| Temperature (°C) | 38.3 [38.0–38.6] | 38.3 [37.6–39.0] | 0.94 |
| Hemoglobin (g/dL) | 13.8 [11.9–14.5] | 12.2 [11.0–13.4] | 0.01 |
| Packed cell volume | 40.7 [35.0–44.0] | 37.0 [33.5–41.0] | 0.02 |
| Mean cell volume | 81.0 [76.0–83.0] | 78.0 [70.9–83.0] | 0.36 |
| Mean cell hemoglobin | 28.0 [26.0–31.0] | 26.3 [24.0–29.0] | 0.06 |
| Mean cell hemoglobin concentration | 33.4 [32.0–34.0] | 32.2 [31.0–33.7] | 0.22 |
| Red blood cells | 5.0 [4.8–5.4] | 4.8 [4.4–5.4] | 0.27 |
| Platelets (×109/L) | 156.0 [73.0–205.0] | 212.0 [162.0–268.0] | 0.002 |
| Thrombocytopenic (platelets < 100 × 109/L) | 7/21 (33.3) | 9/101 (8.9) | 0.01 |
| Total white blood cells (×109/L) | 5.3 [4.7–9.6] | 7.7 [5.7–10.8] | 0.06 |
| Neutrophils (%) | 52.0 [34.0–71.9] | 65.0 [57.0–76.0] | 0.02 |
| Lymphocytes (%) | 37.0 [15.0–45.0] | 23.0 [13.0–33.0] | 0.08 |
| Monocytes (%) | 13.0 [9.0–16.0] | 9.0 [6.0–11.0] | 0.002 |
| Eosinophils (%) | 0.8 [0.0–1.3] | 1.8 [0.4–4.0] | 0.008 |
| Urea (mmol/L) | 4.9 [3.5–5.7] | 3.8 [2.8–5.1] | 0.06 |
| Creatinine (mmol/L) | 80.0 [44.0–106.5] | 67.0 [45.0–93.0] | 0.51 |
| Sodium (mmol/L) | 137.0 [134.0–140.0] | 140.0 [138.0–142.0] | 0.01 |
| Potassium (mmol/L) | 4.1 [3.7–4.5] | 4.0 [3.7–4.3] | 0.44 |
| Chloride (mmol/L) | 104.0 [102.0–106.0] | 106.0 [104–109] | 0.04 |
| AST (U/L) | 75.0 [36.0–129.5] | 42.0 [31.0–66.0] | 0.09 |
| Alanine aminotransferase (U/L) | 40.0 [28.5–66.0] | 37.0 [25.0–55.0] | 0.64 |
| Alkaline phosphatase (U/L) | 104.5 [75.5–203.5] | 111.0 [76.0–213.0] | 0.58 |
| Total protein (g/L) | 79.5 [72.5–83.0] | 77.0 [72.0–81.0] | 0.35 |
| Albumin (g/L) | 38.0 [34.0–42.0] | 40.0 [36.0–43.0] | 0.25 |
| Positive blood culture | 0/14 (0) | 0/66 (0) | − |
Data are numbers (percentages) or medians [interquartile ranges].