Table 1.
Demographics and Characteristics of Derivation Serum Cohort
| N | 82 |
| Age, yr | 59.8 ± 13.4 |
| Female, n (%) | 65 (80) |
| Race, EA/AA/other, n (%) | 68/12/2 (82.9/14.6/2.4) |
| IPAH/CTD-PAH, n (%) | 37/45 (45/54) |
| 6 MWD, mean (range), m | 384 (211–671) |
| NYHA-FC, n (%) | |
| I | 11 (13.7) |
| II | 37 (45.1) |
| III | 30 (36.6) |
| IV | 4 (9.0) |
| Laboratory chemistries, mean (range) | |
| Serum sodium | 139 (123–147) |
| Serum creatinine | 1.0 (0.4–2.4) |
| NT-proBNP, pg/ml | 2,021 (20–11,698) |
| Hemodynamics | |
| RAP, mm Hg | 8 ± 5 |
| mPAP, mm Hg | 43 ± 14 |
| PCWP, mm Hg | 11 ± 4 |
| PVR, Wood units | 9.4 ± 6.3 |
| CO, L/min | 4.8 ± 1.6 |
| Cardiac index, L/min/m2 | 2.6 ± 0.7 |
Definition of abbreviations: 6 MWD = 6-minute-walk distance; AA = African American; CO = cardiac output; CTD-PAH = connective tissue disease–associated pulmonary arterial hypertension; EA = European American; IPAH = idiopathic pulmonary arterial hypertension; mPAP = mean pulmonary artery pressure; NT-proBNP = N-terminal pro-brain natriuretic peptide; NYHA-FC = New York Heart Association functional class; PCWP = pulmonary capillary wedge pressure; PVR = pulmonary vascular resistance; RAP = right atrial pressure.
Data expressed as mean ± SD unless otherwise indicated.