Table 2.
Correlation Coefficient |
|||
---|---|---|---|
Derivation Cohort |
Multicenter Cohort (Derivation and Validation) |
||
Group I (n = 82) | Group I (n = 132) | IPAH Only (n = 87) | |
Hemodynamics | |||
RAP, mm Hg | 0.1* | 0.2* | 0.3† |
mPAP, mm Hg | 0.2* | 0.3‡ | 0.5§ |
PVR, Wood units | 0.2* | 0.3‡ | 0.5§ |
CO, L/min | −0.2* | −0.2† | −0.3‡ |
Cardiac index, L/min/m2 | −0.2* | −0.2† | −0.3† |
Demographics | |||
Age, yr | 0.3† | 0.2* | 0.03* |
6 MWD, m | −0.4§ | |
|
NYHA-FC | 0.5§ | |
|
Laboratory chemistries | |||
Serum sodium | −0.2† | |
|
Serum creatinine | 0.3† | |
|
NT-proBNP, pg/ml | 0.4† |
Definitions of abbreviations: 6 MWD = 6-minute-walk distance; CO = cardiac output; IPAH = idiopathic pulmonary arterial hypertension; mPAP = mean pulmonary artery pressure; NT-proBNP = N-terminal pro-brain natriuretic peptide; NYHA-FC = New York Heart Association functional class; PVR = pulmonary vascular resistance; RAP = right atrial pressure.
P ≥ 0.05.
P < 0.05.
P < 0.005.
P < 0.001.