Table 5.
Multivariable Cox Proportional Hazard Ratio Models
| HR (95% CI) | |||
|---|---|---|---|
| Genotype (GG) protein D/D104ES | 2.0 (1.1–3.9)* |
||
| Model adjusted for: | Age, Cardiac Index, and | Age, CTD-PAH, and | Sex, CTD-PAH, and |
| Age | — | — | 2.4 (1.2–4.8)* |
| Sex | 3.2 (1.5–7.0)† | 2.4 (1.2–4.8)* | — |
| CTD-PAH | 3.2 (1.5–6.9)† | — | — |
| RAP | 3.0 (1.3–6.8)† | 2.4 (1.2–5.0)* | 2.2 (1.1–4.6)* |
| PVR | 2.8 (1.3–6.2)† | 2.8 (1.4–5.9)† | 2.2 (1.1–4.6)* |
| Cardiac index | — | 3.2 (1.5–6.7)† | 2.9 (1.4–6.3)† |
Definition of abbreviations: CI = confidence interval; CTD-PAH = connective tissue disease–associated pulmonary arterial hypertension; HR = hazard ratio; PVR = pulmonary vascular resistance; RAP = right atrial pressure.
*
P < 0.05.
†
P < 0.01.