Table 1.
Genotype and allele frequency of all three genetic polymorphisms.
| Gene Polymorphisms | Genotypes | ESRD (n = 150) n (%) | Controls (n = 150) n (%) | p Value |
|---|---|---|---|---|
|
| ||||
| c.894G>T | GG | 45 (30.00) | 45 (30.00) | |
| GT | 97 (64.67) | 98 (65.33) | 0.965a | |
| TT | 8 (5.33) | 7 (4.67) | ||
|
| ||||
| Alleles | G | 187 (62.33) | 188 (62.67) | 0.933a |
| T | 113 (37.67) | 112 (37.33) | ||
|
| ||||
| OR (95% CI) | 0.6664 (0.708–1.372) | |||
|
| ||||
| VNTR in intron 4 genotypes | 4b/b | 131 (87.33) | 119 (79.33) | 0.177a |
| 4b/a | 17 (11.33) | 28 (18.67) | ||
| 4a/a | 2 (1.33) | 3 (2.00) | ||
|
| ||||
| Alleles | b | 279 (93.00) | 266 (88.67) | 0.066a |
| a | 21 (7.00) | 34 (11.33) | ||
|
| ||||
| OR (95% CI) | 0.708 (0.289–0.870) | |||
|
| ||||
| c.181C>T | CC | 144 (96.00) | 148 (98.00) | 0.152b |
| CT | 6 (4.00) | 2 (2.00) | ||
| TT | 0 (0.00) | 0 (0.00) | ||
|
| ||||
| Alleles | C | 294 (98.00) | 298 (99.00) | 0.155b |
| T | 6 (2.00) | 2 (1.00) | ||
|
| ||||
| OR (95% CI) | 0.329 (0.066–1.643) | |||
OR: Odds ratio; 95% CI: 95% confidence interval.
a
Data were evaluated by the Pearson χ2 test and were not significant (p >0.05).
b
Data was analyzed excluding the TT genotype.