Table 1.
Demographic and clinical data
| MTLE W | MTLE + D | MTLE + P | Controls | Statistics | |
|---|---|---|---|---|---|
| Male (n) | 10 | 5 | 8 | 11 | No difference |
| Female (n) | 7 | 10 | 3 | 3 | |
| IPI present (n) | 7 | 10 | 8 | n.a. | No difference |
| IPI absent (n) | 10 | 5 | 3 | n.a. | |
| Age of first seizure (years) | 3.8 ± 3.3 | 6.3 ± 7.5 | 7.4 ± 8.5 | n.a. | No difference |
| Age when seizures became recurrent or age of onset (years) | 10.0 ± 5.4 | 12.0 ± 9.7 | 13.5 ± 7.7 | n.a. | No difference |
| Seizure type: CPS (n) | 7 | 9 | 5 | n.a. | No difference |
| Seizure type: SGS (n) | 10 | 6 | 6 | n.a. | |
| Seizure frequency (monthly) | 14.3 ± 11.4 | 12.6 ± 8.9 | 16.4 ± 11.2 | n.a. | No difference |
| Right HS (n) | 12 | 9 | 5 | n.a. | No difference |
| Left HS (n) | 5 | 4 | 5 | n.a. | |
| Bilateral HS (n) | 0 | 2 | 1 | n.a. | |
| Right handedness (n) | 14 | 14 | 11 | n.a. | No difference |
| Left handedness (n) | 2 | 0 | 0 | n.a. | |
| Bilateral handedness (n) | 1 | 1 | 0 | n.a. | |
| Memory in verbal tasks: average or above (n) | 7 | 7 | 2 | n.a. | No difference |
| Memory in verbal tasks: below average (n) | 10 | 8 | 9 | n.a. | |
| Memory in non-verbal tasks: average or above (n) | 11 | 9 | 3 | n.a. | No difference |
| Memory in non-verbal tasks: below average (n) | 6 | 6 | 8 | n.a. | |
| Full-scale IQ | 85.9 ± 7.7 | 84.9 ± 9.3 | 83.4 ± 7.1 | n.a. | No difference |
| Years at school | 7.1 ± 3.5 | 5.5 ± 3.5 | 6.3 ± 4.1 | n.a. | No difference |
| Age at surgery (or at death for controls) (years) | 33.5 ± 8.0 | 37.6 ± 11.7 | 40.0 ± 5.9 | 42.6 ± 16.0 | No difference |
| Duration of epilepsy (years) | 23.9 ± 8.2 | 24.9 ± 13.6 | 26.4 ± 8.6 | n.a. | No difference |
| Collected side: right (n) | 12 | 11 | 6 | 6 | No difference |
| Collected side: left (n) | 5 | 4 | 5 | 8 | |
| Surgical outcome: complete remission (n) | 15 | 10 | 9 | n.a. | No difference |
| Surgical outcome: only auras and/or fewer seizures (n) | 2 | 5 | 2 | n.a. |
Values indicated as mean ± standard deviation when applicable. CPS: Complex partial seizure; HS: Hippocampal sclerosis; IPI: Initial precipitant injury; MTLE: mesial temporal lobe epilepsy; MTLE + D: MTLE + major depression; MTLE + P: MTLE + interictal psychosis; MTLEW: MTLE subjects without psychiatric history; n.a.: Not applicable; SGS: Secondarily generalized seizures.