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Effect of exogenous substance P (SP; 10−3 M) on pyloric circular muscle contractility and p-MLC20 expression following injection of BoNT/A. A and B: pyloric circular muscle contractility to ACh. C: dose response to SP in normal pyloric circular muscle contractility. D and E: p-MLC20 expression following injection of BoNT/A. Results were expressed as means ± SE, means of 5 experiments (total N = 15); *P < 0.05.
