Table 5.

Urinary excretion of citrulline and L-Arg factored for body weight at baseline and during citrulline infusion

	Sham (n = 7)	1–2 Wk (n = 11)	4–5 Wk (n = 7)	10–12 Wk (n = 17)
Citrulline excretion, pg·min−1·100 g BW−1
Baseline	3.7±1.1	12.7±3.8†	1.3±0.1	4.8±1.1
Citrulline infusion	4.2±1.1	10.0±2.7†	1.5±0.3	4.0±0.7
	NS	NS	NS	NS
Arginine excretion, pg·min−1·100 g BW−1
Baseline	0.7±0.2	0.6±0.1	0.3±0.1	1.2±0.3*
Citrulline infusion	1.4±0.3	0.8±0.2	0.5±0.1	1.0±0.2
	P < 0.01	NS	NS	NS

Values are means ± SE. n = No. of rats. Statistics comparing each injury group with sham were done with 1-way ANOVA. Statistics comparing baseline vs. infusion were done with paired t-test.

^*P < 0.01,

^†P < 0.001 vs. sham.