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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Biomaterials. 2014 May 21;35(25):6838–6849. doi: 10.1016/j.biomaterials.2014.04.115

Figure 4.

Figure 4

Macrophage polarization adjacent to single mesh fibers in uncoated and ECM hydrogel coated mesh. The number of M1 (CD86+/CD68+) and M2 (CD206+/CD68+) macrophages in response to uncoated, UBM-ECM dry coated, UBM-ECM wet coated, D-ECM dry coated, and D-ECM wet coated polypropylene mesh were quantified from high magnification images of implanted mesh adjacent to single fibers. Total M1 and M2 macrophages were counted at each increasing distance interval from the mesh fiber surface (ring 1-5) at 3, 7, 14, and 35 day time points. Statistical significant differences were determined with ANOVA (p < 0.05) and denoted with (*) as different from uncoated mesh, or ($) as different between ECM coating groups.