Table 1.
Details of the JEQS2010 Panel
| DRM of PI | DRM of RTI | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Sample number | Subtypea | HIV RNA (log cp/ml) | Type | Major | Minor | Others | NRTIs | NNRTIs | Others |
| 014 | B | 3.07 | Single | D30N, M46I, I54V, V82A, N88D | L10F, L33I, A71V, T74S | I13V, L19I, A22V, E35D, M36I, R41K, I62V, L63P, Q92K, I93L | M41L, L74I, V118I, M184V, T215Y | None | V35K, T39A, K43Q, K122E, I135T, I142T, Q207E, R211K |
| 015 | B | 3.34 | Single | None | None | T12S, I15V, L63P | None | None | K13R, K122E, T200I |
| 016 | B | 2.83 | Single | None | None | T12S, I15V, L63P | None | None | K13R, K122E, T200I |
| 026 | B | 4.70 | 30% mix | (M46ML, V82VT, L90LM)b | (A71AV, T74TS)b | (L10LH, I15VI, K20KR, E35ED, M36MI, N37NE, K43KR, R57RK, D60ED, I62IV, L63P, I64IV, I72IV, Q92EQ, I93IL)b | (D67DN, K70KR, V118VI, M184MV, L210LF, T215TF, K219KE)b | None | (V35VT, T39TA, V60IV, K64KR, K122KE, I135TI, D123DE, M164VM, Q174H, D177DE, Q197QK, T200IA, I202IV, Q207E, R211KR, F214FL)b |
| 028 | B | 4.82 | 10% mix | ||||||
| 029 | B | 5.09 | 50% mix | ||||||
a
Subtype was identified by the NCBI genotyping tool.
b
First amino acid harbored in the majority, second one in the minority (e.g., M46ML, the majority is “M” and the minority is “L”).
DRM, drug-resistance mutation; PI, protease inhibitor; RTI, reverse transcriptase inhibitor; NRTIs, nucleoside analogue reverse transcriptase inhibitors; NNRTIs, nonnucleoside analogue reverse transcriptase inhibitors; Single, single variant.