Table 3.
Demographic Characteristics of the MESA cohort (Including the optional statin eligibility criteria for ATP III and New ACC/AHA 2013 guidelines)
| Variable | Total MESA Sample (N=5437) | Recommended for Statin Therapy Under the NCEP/ATPIII Guidelines (N=1624) | Recommended for Statin Therapy Under the New AHA/ACC 2013 Guidelines (N=3610) | Net MESA Participants Recommended Statin Therapy (N=2012) |
|---|---|---|---|---|
| Age (years) | 61.4 ±10.3 | 65.5 ±9.6 | 66.0 ±9.1 | 66.2 ±8.8 |
| Female (%) | 2845(52.3) | 507(31.2) | 1523(42.2) | 1034(51.4) |
| Race/Ethnicity (%) | ||||
| Caucasian | 2055(37.8) | 507(31.2) | 1265(35.0) | 771(38.3) |
| Chinese | 672(12.4) | 180(11.1) | 406(11.3) | 227(11.3) |
| African American | 1482(27.3) | 498(30.7) | 1148(31.8) | 655(32.6) |
| Hispanic | 1228(22.6) | 439(27.0) | 791(21.9) | 359(17.8) |
| BMI( Kg/m2) | 28.2 ±5.5 | 29.1 ±5.2 | 28.4 ±5.2 | 27.8 ±5.2 |
| Diabetes Mellitus (%) | 575(10.6) | 575(35.4) | 575(15.9) | 0(0.0) |
| Cholesterol(mg/dl) | ||||
| Total | 195.6 ±34.4 | 205.9 ±37.6 | 197.1 ±35.8 | 190.7 ±33.0 |
| LDL | 119.5 ±31.2 | 132.9 ±34.0 | 121.8 ±32.5 | 113.4 ±28.8 |
| HDL | 51.2 ±15.0 | 44.3 ±10.8 | 49.4 ±14.4 | 53.4 ±15.5 |
| Triglycerides | 125.0 ±65.5 | 143.9 ±68.1 | 130.2 ±67.5 | 119.2 ±64.9 |
| Blood Pressure(mmHg) | ||||
| Systolic | 125.7 ±21.3 | 134.2 ±22.0 | 132.2 ±21.1 | 130.3 ±20.2 |
| Diastolic | 72.0 ±10.3 | 74.8 ±10.3 | 73.6 ±10.3 | 72.6 ±10.3 |
| Cigarette Smoking (%) | ||||
| Never | 2750(50.6) | 685(42.2) | 1661(46.0) | 990(49.2) |
| Former | 1966(36.2) | 632(38.9) | 1382(38.3) | 759(37.7) |
| Current | 721(13.3) | 307(18.9) | 567(15.7) | 263(13.1) |
| Antihypertensive Medication use (%) | 1765(32.5) | 805(49.6) | 1514(41.9) | 713(35.4) |
| Statin use (%) | 0(0.0) | 0(0.0) | 0(0.0) | 0(0.0) |
| NCEP/ATP III Risk Score (%) | 8.0 ±7.8 | 14.6 ±8.2 | 11.2 ±7.7 | 8.5 ± 6.0 |
| Low Risk (<10%) | 3719(68.4) | 449(27.7) | 1892(52.4) | 1469(73.0) |
| Intermediate Risk (10-20%) | 1227(22.6) | 788(48.5) | 1227(34.0) | 439(21.8) |
| High Risk (>20%) | 491(9.0) | 387(23.8) | 491(13.6) | 104(5.2) |
| ASCVD Risk Score (%) | 12.6 ±12.7 | 22.1 ±14.5 | 17.9 ±12.8 | |
| Low Risk (<7.5%) | 2540(46.7) | 182(11.2) | 713(19.8) | 557(27.7) |
| High Risk (≥ 7.5%) | 2897(53.3) | 1442(88.8) | 2897(80.3) | 1455(72.3) |
| ASCVD Event (%) | 318(5.9) | 166(10.2) | 291(8.1) | 126(6.3) |
Footnote: BMI indicates body mass index; NCEP indicates National Cholesterol Education Program; ATP indicates Adult Treatment Program; ASCVD indicated Atherosclerotic cardiovascular disease.