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. 2015 Mar 1;32(5):342–352. doi: 10.1089/neu.2014.3548

FIG. 3.

FIG. 3.

Enhanced immunoassay using multi-arrayed fiberoptics (EIMAF; ––) vs. sandwich enzyme-linked immunosorbent assay (ELISA; – –) for T-tau (●, ■) and P-tau (○, □) detection sensitivity. Detection of T-tau and P-tau was performed using serial dilutions of JNPL3 (P301L; ●, ○) and T-tau knockout (TauKO; ■, □) mouse brain homogenates. EIMAF has a fivefold to sixfold more sensitive detection limit than sandwich ELISA.